A2V Aminos and Peptides
Melanotan I 10mg
Melanotan I 10mg
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Melanotan I Peptide
For Research Use Only – Not for Human Consumption
Supplied by A2V Aminos and Peptides
Product Overview
Melanotan I, also known as Afamelanotide, is a synthetic analogue of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It is a linear peptide designed to stimulate melanin production in the skin, promoting tanning and providing photoprotection. Melanotan I has been researched for therapeutic potential in conditions like erythropoietic protoporphyria (EPP) and other pigmentary disorders due to its ability to increase skin pigmentation and reduce sensitivity to ultraviolet radiation.
Mechanism of Action
Melanotan I functions primarily by activating the melanocortin 1 receptor (MC1R) on melanocytes, stimulating the production of melanin pigment. This increase in melanin helps protect the skin from UV damage. Compared to Melanotan II, Melanotan I is less active at other melanocortin receptors, leading to fewer systemic side effects, making it a targeted agent for skin pigmentation.
Research Applications
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Photoprotection: Investigated for protecting skin from UV-induced damage by increasing melanin levels.
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Pigmentary Disorders: Explored as a treatment option for disorders such as erythropoietic protoporphyria (EPP) and vitiligo.
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Skin Tanning: Studied for its ability to induce a natural-looking tan in research models.
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Potential Anti-Inflammatory Effects: Early research suggests possible modulation of inflammatory pathways linked to skin conditions.
Peptide Stacking Considerations
Melanotan I’s focused activity on MC1R makes it a candidate for studies focusing solely on pigmentation without broader systemic effects. Its combination with other peptides is less common but could be investigated in contexts involving skin health and repair.
Legal and Regulatory Status in Australia
Melanotan I is a Schedule 4 prescription-only substance in Australia and is not approved by the Therapeutic Goods Administration (TGA) for general human use. It is not included in the Australian Register of Therapeutic Goods (ARTG), and possession or use without appropriate prescription is illegal. The peptide is supplied exclusively for research use. (tga.gov.au, aussiepeptides.com)
Product Specifications
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Purity: ≥98%
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Form: Lyophilized powder
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Available Sizes: 10mg vials
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Storage: Store refrigerated at 2–8°C short term; freeze at -18°C or lower for long-term storage. Protect from light and moisture. (australia.pharmalabglobal.com)
Reconstitution and Handling
Reconstitute by carefully injecting bacteriostatic water slowly along the vial wall to avoid foam. Swirl gently to dissolve the powder; do not shake vigorously. Store reconstituted solution refrigerated and use within 2–4 weeks.
Disclaimer
All products provided by A2V Aminos and Peptides are intended solely for laboratory research purposes. They are not for human or veterinary consumption. Compliance with applicable laws and safety standards is the user’s responsibility.
Note: This information is for educational and research purposes only and does not constitute medical advice. Consult a qualified professional before handling research peptides.

Structure of Melanotan 1
Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.8 g/mol
PubChem CID: 16197727
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